Atropisomerism plays a crucial role in drug development. Molecules with the feature have become more prevalent in the R&D pipeline in recent years, creating both challenges and opportunities for innovator companies and CDMOs alike. The situation is driving demand for companies with mastery of the synthesis and purification capabilities needed to produce safe and effective atropisomers.
The team at Piramal Pharma Solutions’ drug discovery site in Ahmedabad, India regularly faces the many challenges posed by atropisomers when supporting the development of its clients’ drug molecules. As the company has worked through the complications created by the interconverting mixtures, Piramal has accrued deep expertise in how to unlock the potent efficacy of the drug molecules while mitigating the potential risks of unwanted biological activities. Download this white paper to learn more about our capabilities.