Therapeutic peptides are advancing disease treatment by combining the benefits of small molecules and antibodies. Despite their potential, peptides face challenges in oral drug delivery due to instability in the gastrointestinal tract. Recent breakthroughs have produced drugs like semaglutide, showing the promise of peptides. They bind to cell receptors with high specificity, targeting "undruggable" interactions, and offer lower production costs and reduced immunogenicity. However, peptides often degrade quickly and struggle to cross cell membranes, limiting their effectiveness.
To overcome these issues, the drug formulation industry has developed new technologies to improve peptide stability and delivery, making oral peptide products more feasible. For more on therapeutic peptides and recent innovations, read our whitepaper.